Mechanisms of resistance to beta-lactam antibiotics in Acinetobacter calcoaceticus.

doi:10.1093/jac/28.6.791

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Article

Mechanisms of resistance to beta-lactam antibiotics in Acinetobacter calcoaceticus.

The Journal of antimicrobial chemotherapy - 1 Dec 1991

Obara M, Nakae T

Abstract excerpt

Examination of 12 strains of Acinetobacter calcoaceticus revealed that the strains expressed different constitutive levels of beta-lactamase. Mutants resistant to cefoxitin, cefoperazone or ceftazidime were selected from a strain producing a low level of beta-lactamase. All the mutants showed no change in expression of beta-lactamase, but produced penicillin-binding proteins with altered expression and/or...

Topics

Acinetobacter calcoaceticus
Anti-Bacterial Agents
Bacterial Outer Membrane Proteins
Bacterial Proteins
Carrier Proteins
Cell Membrane Permeability
Drug Resistance, Microbial
Hexosyltransferases
Microbial Sensitivity Tests
Muramoylpentapeptide Carboxypeptidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Penicillin-Binding Proteins

Penicillins

Peptidyl Transferases

beta-Lactamases

beta-Lactams

Source

Open in PubMed

Identifiers

PMID: 1816177
DOI: 10.1093/jac/28.6.791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1816177-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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