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Article

Genetic variations of VDR/NR1I1 encoding vitamin D receptor in a Japanese population.

Drug metabolism and pharmacokinetics - 1 Dec 2007

Ukaji Maho, Saito Yoshiro, Fukushima-Uesaka Hiromi, Maekawa Keiko, Katori Noriko, Kaniwa Nahoko, Yoshida Teruhiko, Nokihara Hiroshi, Sekine Ikuo, Kunitoh Hideo, Ohe Yuichiro, Yamamoto Noboru, Tamura Tomohide, Saijo Nagahiro, Sawada Jun-ichi

Abstract excerpt

The vitamin D receptor (VDR) is a transcriptional factor responsive to 1alpha,25-dihydroxyvitamin D(3) and lithocholic acid, and induces expression of drug metabolizing enzymes CYP3A4, CYP2B6 and CYP2C9. In this study, the promoter regions, 14 exons (including 6 exon 1's) and their flanking introns of VDR were comprehensively screened for genetic variations in 107 Japanese subjects. Sixty-one genetic variations...

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Identifiers

PMID: 18159135
DOI: 10.2133/dmpk.22.462

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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