Article
HLA class I polymorphism in the Cuban population.
Human immunology - 1 Nov 2007
Ferrer Annia, Nazábal Marcelo, Companioni Osmel, Fernández de Cossío Maria E, Camacho Hanlet, Cintado Alberto, Benítez Jesús, Casalvilla Racmar, Sautié Miguel, Villareal Adelaida, Díaz Tamara, Marrero Anisley, Fernández de Cossío Jorge, Hodelin Abel, Leal Lester, Ballester Laura, Novoa Lidia I, Middleton Derek, Dueñas Marta
Abstract excerpt
The extreme polymorphism found at some of the human leukocyte antigen (HLA) system loci makes it an invaluable tool for population genetic analyses. In the present study the genetic polymorphism of the Cuban population was estimated at HLA-A, -B, and -Cw loci by DNA typing. HLA class I allele and haplotype diversity were determined in 390 unrelated Cuban individuals (188 whites and 202 mulattos) from all over the...
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