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Article

Clinical and genetic study in Chinese patients with Alexander disease.

Journal of child neurology - 1 Feb 2008

Ye Wu, Qiang Gu, Jingmin Wang, Yanling Yang, Xiru Wu, Yuwu Jiang

Abstract excerpt

Alexander disease is a rare progressive leukoencephalopathy inherited in an autosomal dominant manner. The infantile form is the most common, with onset before 2 years of age. The typical clinical signs include psychomotor retardation and regression, seizures, and megalencephaly. Juvenile and adult forms are also recognized. The neuropathology of Alexander disease is characterized by abundant presence of...

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Identifiers

PMID: 18079314
DOI: 10.1177/0883073807308691

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Clinical and genetic study in Chinese patients with Alexander disease.PMID 18079314Read ↗

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