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The Essential Human Cytomegalovirus Gene UL52 Is Required for Cleavage-Packaging of the Viral Genome

13 Dec 2007

Abstract excerpt

Replication of human cytomegalovirus (HCMV) produces large DNA concatemers of head-to-tail-linked viral genomes that upon packaging into capsids are cut into unit-length genomes. The mechanisms underlying cleavage-packaging and the subsequent steps prior to nuclear egress of DNA-filled capsids are incompletely understood. The hitherto uncharacterized product of the essential HCMV UL52 gene was proposed to...

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PMID: 18077717
DOI: 10.1128/jvi.01967-07

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The Essential Human Cytomegalovirus Gene UL52 Is Required for Cleavage-Packaging of the Viral GenomePMID 18077717Read ↗

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