Article
Deletion of tandem repeats causes flocculation phenotype conversion from Flo1 to NewFlo in Saccharomyces cerevisiae.
Journal of molecular microbiology and biotechnology - 1 Jan 2009
Liu Nan, Wang Dong-li, Wang Zhao-yue, He Xiu-ping, Zhang Bo-run
Abstract excerpt
A gene, FLONS, conferring NewFlo-type flocculation ability in yeast was cloned. The 3,396-bp ORF encoded a peptide of 1,132 amino acids with high identity to Flo1 protein. Aligned with the FLO1 gene, two repeated regions (675 and 540 bp) were lost in the middle of FLONS, revealing that this gene was a derived form of the FLO1 gene. The missing repeated sequence contained three highly homologous repeat units....
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