Article
Angiotensin-converting enzyme insertion/deletion gene polymorphism in inflammatory bowel diseases.
European journal of gastroenterology & hepatology - 1 Nov 2007
Saibeni Simone, Spina Luisa, Virgilio Tiziana, Folcioni Anna, Borsi Greta, de Franchis Roberto, Cugno Massimo, Vecchi Maurizio
Abstract excerpt
INTRODUCTION: The renin-angiotensin system is strictly related to the kallikrein-kinin system and both are involved in many physiological and disease conditions and possibly in the pathogenesis of inflammatory bowel disease (IBD). Angiotensin-converting enzyme (ACE) is the pivotal enzyme of the renin-angiotensin system and the main catabolic enzyme of the kallikrein-kinin system. The ACE I/D (insertion/deletion)...
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