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Molecular Basis of Commensalism in the Urinary Tract: Low Virulence or Virulence Attenuation?

27 Nov 2007

Abstract excerpt

In some patients, Escherichia coli strains establish significant bacteriuria without causing symptoms of urinary tract infection (UTI). These asymptomatic-bacteriuria (ABU) strains have been shown to express fewer virulence factors than the uropathogenic E. coli (UPEC) strains that cause severe, symptomatic UTI. Paradoxically, ABU strains carry many typical UPEC virulence genes, and the molecular basis of their...

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PMID: 18039831
DOI: 10.1128/iai.01215-07

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