Article
Mutations in the periplasmic chaperone leading to loss of surface expression of the colonization factor CS6 in enterotoxigenic Escherichia coli (ETEC) clinical isolates.
Microbial pathogenesis - 1 Mar 2008
Nicklasson Matilda, Sjöling Asa, Lebens Michael, Tobias Joshua, Janzon Anders, Brive Lars, Svennerholm Ann-Mari
Abstract excerpt
Enterotoxigenic Escherichia coli (ETEC) cause diarrhoea by adhesion to human enterocytes by one or more colonization factors (CFs) and secretion of heat-labile (LT) and/or heat-stable (ST) enterotoxins. Expression of coli surface antigen 6 (CS6) on the bacterial surface, usually associated with ETEC strains that produce ST alone or in combination with LT, is rarely found in strains expressing only LT. However, a...
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