Article
Ck5-positive cells are precursor cells of glandular and myoepithelial cell lineages in the human breast epithelium. A new cell concept as a basis for a better understanding of proliferative breast disease?
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 2005
Böcker W, Bürger H, Buchwalow I B, Decker T
Abstract excerpt
The question of whether stem cells exist in the human breast has never been satisfactorily resolved. Using a double immunofluorescence technique for simultaneous demonstration of cytokeratin subgroups 5, 8/18/19 and the differentiation marker smooth muscle actin, we provided direct evidence of the existence of a Ck5-positive cells that differentiate to either the glandular or myoepithelial cell lineage via...
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