Article
Optimisation of hydrocortisone production by Curvularia lunata.
Applied biochemistry and biotechnology - 1 Jul 2007
Lu Wenyu, Du Lianxiang, Wang Min, Jia Xiaoqiang, Wen Jianping, Huang Yuping, Guo Yawen, Gong Wei, Bao Huike, Yang Jing, Sun Bing
Abstract excerpt
A new method for breeding the hydrocortisone overproducing strain Curvularia lunata by screening ketoconazole-resistance mutant was developed. A hydrocortisone overproducing mutant C. lunata KA-91 with ketoconazole-resistance marker was obtained from protoplasts treated with ultraviolet radiation...
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