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Article

Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.

The Journal of cell biology - 19 Nov 2007

Ilani Tal, Khanna Chand, Zhou Ming, Veenstra Timothy D, Bretscher Anthony

Abstract excerpt

Immunological synapse (IS) formation involves receptor-ligand pair clustering and intracellular signaling molecule recruitment with a coincident removal of other membrane proteins away from the IS. As microfilament-membrane linkage is critical to this process, we investigated the involvement of ezrin and moesin, the two ezrin/radixin/moesin proteins expressed in T cells. We demonstrate that ezrin and moesin,...

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Identifiers

PMID: 18025306
DOI: 10.1083/jcb.200707199
PMCID: PMC2080902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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