Article
Population-based analysis of left- and right-sided diaphragmatic hernias demonstrates different frequencies of selected additional anomalies.
American journal of medical genetics. Part A - 15 Dec 2007
Slavotinek Anne M, Warmerdam Barbara, Lin Angela E, Shaw Gary M
Abstract excerpt
Congenital diaphragmatic hernia (CDH) is a common birth defect that can be subdivided into several different types depending on the anatomical structures affected. Several studies have demonstrated that right-sided CDH (R-CDH) and left-sided CDH (L-CDH) in humans are associated with different clinical presentations and outcomes. We hypothesized that R-CDH and L-CDH are phenotypically and pathogenically distinct,...
Topics
- Abnormalities, Multiple
- Cardiovascular Abnormalities
- Chromosome Mapping
- Congenital Abnormalities
- Extremities
- Female
- Hernia, Diaphragmatic
- Humans
- Infant
- Infant, Newborn
- Lung
- Male
- Models, Statistical
- Phenotype
- Respiratory System Abnormalities
- Urogenital Abnormalities