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Article

The developmental selector AS1 is an evolutionarily conserved regulator of the plant immune response.

Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2007

Nurmberg Pedro L, Knox Kirsten A, Yun Byung-Wook, Morris Peter C, Shafiei Reza, Hudson Andrew, Loake Gary J

Abstract excerpt

The MYB-related gene ASYMMETRIC LEAVES 1 (AS1) and its orthologs have an evolutionarily conserved role in specification of leaf cell identity. AS1 is expressed in leaf founder cells, where it functions as a heterodimer with the structurally unrelated AS2 proteins to repress activity of KNOTTED 1-like homeobox (KNOX) genes. AS1 therefore confines KNOX activity to the shoot apical meristem, where it promotes stem...

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Identifiers

PMID: 18003921
DOI: 10.1073/pnas.0705586104
PMCID: PMC2141856

Genes

MYB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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