Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NF-kappaB/Rel-mediated regulation of the neural fate in Drosophila.

PloS one - 14 Nov 2007

Ayyar Savita, Pistillo Daniela, Calleja Manuel, Brookfield Anna, Gittins Kelly, Goldstone Claire, Simpson Pat

Abstract excerpt

Two distinct roles are described for Dorsal, Dif and Relish, the three NF-kappaB/Rel proteins of Drosophila, in the development of the peripheral nervous system. First, these factors regulate transcription of scute during the singling out of sensory organ precursors from clusters of cells expressing the proneural genes achaete and scute. This effect is possibly mediated through binding sites for NF-kappaB/Rel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to Drosophila
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nervous System

Share to NF-kappa B

Source

Open in PubMed Open full text

Identifiers

PMID: 18000549
DOI: 10.1371/journal.pone.0001178
PMCID: PMC2064963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NF-kappaB/Rel-mediated regulation of the neural fate in Drosophila.PMID 18000549Read ↗

The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes.Semantic proximity Read ↗

phyllopod is a target gene of proneural proteins in Drosophila external sensory organ development.Semantic proximity Read ↗

Alternative pathway of cell death in Drosophila mediated by NF-κB transcription factor Relish.Semantic proximity Read ↗

Down-Regulation of NF-κB Target Genes by the AP-1 and STAT Complex during the Innate Immune Response in DrosophilaSemantic proximity Read ↗

AP-1, but not NF-kappa B, is required for efficient steroid-triggered cell death in Drosophila.Semantic proximity Read ↗

Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification.Semantic proximity Read ↗

asense is a Drosophila neural precursor gene and is capable of initiating sense organ formation.Semantic proximity Read ↗

Persistent expression of genes of the enhancer of split complex suppresses neural development in Drosophila.Semantic proximity Read ↗

Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila.Semantic proximity Read ↗

Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.Semantic proximity Read ↗

The NFκB <i>Dif</i> is required for behavioral and molecular correlates of sleep homeostasis in <i>Drosophila</i>Semantic proximity Read ↗

The selector gene cut represses a neural cell fate that is specified independently of the Achaete-Scute-Complex and atonal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.