Article
A novel population of repair cells identified in the stroma of the human cornea.
Stem cells and development - 1 Oct 2007
Thill Michelle, Schlagner Kathleen, Altenähr Sybille, Ergün Süleyman, Faragher Richard G A, Kilic Nerbil, Bednarz Jürgen, Vohwinkel Gabi, Rogiers Xavier, Hossfeld Dieter K, Richard Gisbert, Gehling Ursula M
Abstract excerpt
The transmembrane protein CD133 is expressed on somatic stem cells of various adult human tissues. To investigate whether human corneal stroma also contains CD133-expressing cells and to analyze their functional features, stromal cells were isolated by collagenase digestion, immunophenotyped, and transferred to different culture systems to determine their stem cell properties as well as their differentiation...
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