Article
Molecular origin of the self-assembly of lanreotide into nanotubes: a mutational approach.
Biophysical journal - 1 Mar 2008
Valéry Céline, Pouget Emilie, Pandit Anjali, Verbavatz Jean-Marc, Bordes Luc, Boisdé Isabelle, Cherif-Cheikh Roland, Artzner Franck, Paternostre Maité
Abstract excerpt
Lanreotide, a synthetic, therapeutic octapeptide analog of somatostatin, self-assembles in water into perfectly hollow and monodisperse (24-nm wide) nanotubes. Lanreotide is a cyclic octapeptide that contains three aromatic residues. The molecular packing of the peptide in the walls of a nanotube...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
