Article
[Genetic susceptibility to Andes Hantavirus: Association between severity of disease and HLA alíeles in Chilean patients].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia - 1 Oct 2007
Ferrer C Pablo, Vial C Pablo A, Ferrés G Marcela, Godoy M Paula, Culza V Analla, Marco C Claudia, Castillo H Constanza, Umaña C María Elena, Rothhammer E Francisco, Llop R Elena
Abstract excerpt
Andes hantavirus (ANDV) infection in Chile has a variable clinical expression, and infected individuals may present with different grades of disease severity. This study aimed to determine if clinical expression of ANDV infection in Chilean patients is associated with the HLA system. HLA alíeles A, B, DRB1 and DQB1, were studied in two groups of patients with confirmed ANDV infection: 41 patients with a mild...
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