Article
Haplotypes of PADI4 susceptible to rheumatoid arthritis are also associated with ulcerative colitis in the Japanese population.
Clinical immunology (Orlando, Fla.) - 1 Feb 2008
Chen Chun Chuan, Isomoto Hajime, Narumi Yukiko, Sato Kayoko, Oishi Yuuki, Kobayashi Tsutomu, Yanagihara Katsunori, Mizuta Yohei, Kohno Shigeru, Tsukamoto Kazuhiro
Abstract excerpt
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder characterized by intractable inflammation specific to the gastrointestinal tract. The precise etiology of IBD remains unknown. Recently, haplotypes of peptidylarginine deiminase type 4 (PADI4) have been identified as the rheumatoid arthritis (RA)-susceptible gene. PADI4 is located at...
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