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Article

Enantioselective Oxidation of Enterodiol to Enterolactone by Human Intestinal Bacteria

1 Jan 2007

Abstract excerpt

In the course of our experiments on the metabolic conversion of lignans to the estrogenic substances enterodiol (END) and enterolactone (ENL) by human intestinal flora, we isolated two anaerobes, Ruminococcus sp. END-1 and strain END-2, capable of oxidizing END. The former selectively converted (-)-END to (-)-ENL, while the latter selectively converted (+)-END to (+)-ENL, indicating enantioselective oxidation by...

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Identifiers

PMID: 17978502
DOI: 10.1248/bpb.30.2204

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