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Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples

30 Oct 2007

Abstract excerpt

Microarray technology is a powerful tool in the discovery of new biomarkers for disease. After solid organ transplantation, where the detection of rejection is usually made on invasive biopsies, it could be hypothesized that noninvasive transcriptional profiling of peripheral blood will reveal rejection-specific expression patterns from circulating immune cells. However, in kidney transplant rejection, the...

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PMID: 17971501
DOI: 10.1152/physiolgenomics.00216.2007

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