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Article

Multiple colorectal neoplasms in X-linked agammaglobulinemia.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Jan 2008

Brosens Lodewijk A A, Tytgat Kristien M A J, Morsink Folkert H M, Sinke Richard J, Ten Berge Ineke J M, Giardiello Francis M, Offerhaus G Johan A, Keller Josbert J

Abstract excerpt

X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder caused by germline mutation of the Bruton tyrosine kinase (BTK) gene. It is characterized by disturbed B-cell development, decreased immunoglobulin levels, and increased patient susceptibility to infection. An increased risk of cancer has been suggested, but most reports were described before the identification of BTK gene mutation as the...

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Source

Identifiers

PMID: 17967562
DOI: 10.1016/j.cgh.2007.08.019

Genes

BTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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