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Article

LDLR and ApoB are major genetic causes of autosomal dominant hypercholesterolemia in a Taiwanese population.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Oct 2007

Yang Kai-Chien, Su Yi-Ning, Shew Jin-Yuh, Yang Kai-Ying, Tseng Wei-Kung, Wu Chau-Chung, Lee Yuan-Teh

Abstract excerpt

BACKGROUND/PURPOSE: Autosomal dominant hypercholesterolemia (ADH) is an autosomal dominant inherited disease characterized by an increase in low-density lipoprotein cholesterol levels and premature coronary heart disease, which can be caused by mutations in genes encoding the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB) and proprotein convertase subtilisin/kexin type 9 (PCSK9). There is scant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17964958
DOI: 10.1016/S0929-6646(08)60044-3

Genes

LDLR
PCSK9
APOB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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