Detection of the Glanzmann's thrombasthenia mutations in Arab and Iraqi-Jewish patients by polymerase chain reaction and restriction analysis of blood or urine samples.

Article

Detection of the Glanzmann's thrombasthenia mutations in Arab and Iraqi-Jewish patients by polymerase chain reaction and restriction analysis of blood or urine samples.

Thrombosis and haemostasis - 1 Oct 1991

Peretz H, Seligsohn U, Zwang E, Coller B S, Newman P J

Abstract excerpt

Severe Glanzmann's thrombasthenia is relatively frequent in Iraqi-Jews and Arabs residing in Israel. We have recently described the mutations responsible for the disease in Iraqi-Jews--an 11 base pair deletion in exon 12 of the glycoprotein IIIa gene, and in Arabs--a 13 base pair deletion at the...

Topics

Base Sequence
Humans
Iraq
Israel
Jews
Molecular Sequence Data
Mutation
Pedigree
Polymerase Chain Reaction
Restriction Mapping
Thrombasthenia

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