Article
Learning the drug target-likeness of a protein.
Proteomics - 1 Dec 2007
Xu Huan, Xu Hangyang, Lin Mingzhi, Wang Wei, Li Zimu, Huang Jiaju, Chen Yuzong, Chen Xin
Abstract excerpt
Current drug discovery and development approaches rely extensively on the identification and validation of appropriate targets; for example, those with marketable and robust therapeutics. Wide-ranging efforts have been directed at this problem and various approaches have been developed to identify disease-associated genes as candidates. In this work, we show with statistical significance that successful drug...
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