Article
"Paterniplex", a highly discriminative decaplex STR multiplex tailored for investigating special problems in paternity testing.
Electrophoresis - 1 Nov 2007
Betz Thomas, Immel Uta-Dorothee, Kleiber Manfred, Klintschar Michael
Abstract excerpt
The goal of the study was to develop a STR multiplex ("Paterniplex") that is--as supplement to commercially available multiplex kits like the Identifiler kit (Applied Biosystems, Foster City, CA)--suitable for solving complex paternity cases such as deficiency cases or cases with mutations. The Paterniplex comprises the nine highly polymorphic STRs D8S1132, D7S1517, D10S2325, D12S391, Se33, D17S976, Penta E,...
Topics
- Amelogenin
- DNA Fingerprinting
- Female
- Forensic Medicine
- Gene Amplification
- Gene Frequency
- Humans
- Likelihood Functions
- Linkage Disequilibrium
- Male
- Microsatellite Repeats
- Mutation
- Paternity
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Predictive Value of Tests
- Reproducibility of Results
- White People