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Article

The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype.

Biomaterials - 1 Jan 2008

Adelöw Catharina, Segura Tatiana, Hubbell Jeffrey A, Frey Peter

Abstract excerpt

The formation of scar tissue due to dedifferentiation of smooth muscle cells (SMCs) is one of the major issues faced when engineering bladder tissue. Furthermore, cell sources for regenerating the SMC layer are also limiting. Here we explore if human mesenchymal stem cells (MCSs), cultured in enzymatically degradable poly(ethylene glycol) (PEG) hydrogel scaffolds can be differentiated into SMC-like cells. We...

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Source

Identifiers

PMID: 17953986
DOI: 10.1016/j.biomaterials.2007.09.036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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