Article
HPLC determination of hemoglobins to establish reference values with the aid of statistics and informatics.
Genetics and molecular research : GMR - 30 Jun 2007
Ondei L S, Zamaro P J A, Mangonaro P H, Valêncio C R, Bonini-Domingos C R
Abstract excerpt
The purpose of the present study was to establish reference values for hemoglobins (Hb) using HPLC, in samples containing normal Hb (AA), sickle cell trait without alpha-thalassemia (AS), sickle cell trait with alpha-thalassemia (ASH), sickle cell anemia (SS), and Hb SC disease (SC). The blood samples were analyzed by electrophoresis, HPLC and molecular procedures. The Hb A2 mean was 4.30 +/- 0.44% in AS, 4.18...
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