Article
Genotyping of synovial fibroblasts: cDNA array in combination with RAP-PCR in arthritis.
Methods in molecular medicine - 1 Jan 2007
Neumann Elena, Judex Martin, Gay Steffen, Müller-Ladner Ulf
Abstract excerpt
Evaluation of differentially regulated genes is essential for the development of novel therapeutic approaches in multifactorial diseases such as rheumatoid arthritis (RA). RA synovial fibroblasts (RASF) are key players in inflammation and cartilage destruction. Therefore, RASF are important cellular targets for the analysis of gene expression profiles. Such analyses may include a comparison of SF from nontreated...
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