Article
Resistance to bacitracin in Bacillus subtilis: unexpected requirement of the BceAB ABC transporter in the control of expression of its own structural genes.
Journal of bacteriology - 1 Dec 2007
Bernard Remi, Guiseppi Annick, Chippaux Marc, Foglino Maryline, Denizot François
Abstract excerpt
The Bacillus subtilis BceAB ABC transporter involved in a defense mechanism against bacitracin is composed of a membrane-spanning domain and a nucleotide-binding domain. Induction of the structural bceAB genes requires the BceR response regulator and the BceS histidine kinase of a signal transduction system. However, despite the presence of such a transduction system and of bacitracin, no transcription from an...
Topics
- ATP-Binding Cassette Transporters
- Anti-Bacterial Agents
- Bacillus subtilis
- Bacitracin
- Bacterial Proteins
- Drug Resistance, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Mutation
- Promoter Regions, Genetic
- Transcription, Genetic