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Article

Central pontine signal changes in Wilson's disease: distinct MRI morphology and sequential changes with de-coppering therapy.

Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Oct 2007

Sinha Sanjib, Taly Arun B, Ravishankar Shivashankar, Prashanth Lingappa K, Vasudev Mandapati K

Abstract excerpt

BACKGROUND AND PURPOSE: Reports of central pontine myelinolysis (CPM)-like changes in Wilson's disease (WD) and its sequential changes are exceptional. The aim was to study the MRI characteristics of CPM-like changes in WD and the serial changes. METHODS: Among the 121 patients of WD, twenty (M:F:9:11, age at onset: 14.2 +/- 4.6 years) had features similar to CPM. All had progressive neuropsychiatric form of WD....

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Source

Identifiers

PMID: 17894614
DOI: 10.1111/j.1552-6569.2007.00120.x

Genes

CPM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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