Article
Beta-amyloid burden is not associated with rates of brain atrophy.
Annals of neurology - 1 Feb 2008
Josephs Keith A, Whitwell Jennifer L, Ahmed Zeshan, Shiung Maria M, Weigand Stephen D, Knopman David S, Boeve Bradley F, Parisi Joseph E, Petersen Ronald C, Dickson Dennis W, Jack Clifford R
Abstract excerpt
OBJECTIVE: To test the hypothesis that beta-amyloid (Abeta) burden is associated with rates of brain atrophy. METHODS: Forty-five subjects who had been prospectively studied, died, and had an autopsy diagnosis of low, intermediate, or high probability of Alzheimer's disease who had two volumetric...
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