Article
A PINOID-dependent binary switch in apical-basal PIN polar targeting directs auxin efflux.
Science (New York, N.Y.) - 29 Oct 2004
Friml Jirí, Yang Xiong, Michniewicz Marta, Weijers Dolf, Quint Ab, Tietz Olaf, Benjamins René, Ouwerkerk Pieter B F, Ljung Karin, Sandberg Göran, Hooykaas Paul J J, Palme Klaus, Offringa Remko
Abstract excerpt
Polar transport-dependent local accumulation of auxin provides positional cues for multiple plant patterning processes. This directional auxin flow depends on the polar subcellular localization of the PIN auxin efflux regulators. Overexpression of the PINOID protein kinase induces a basal-to-apical shift in PIN localization, resulting in the loss of auxin gradients and strong defects in embryo and seedling roots....
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