Article
The vanishing twin: an explanation for discordance between chorionic villus karyotype and fetal phenotype.
Prenatal diagnosis - 1 Sept 1991
Reddy K S, Petersen M B, Antonarakis S E, Blakemore K J
Abstract excerpt
One 'erroneous' diagnosis occurred in 200 first-trimester chorionic villus samples (CVS) analysed. In direct preparations following 24 h incubation as well as in long-term cultures, a 46,XX karyotype was observed in the villi (28 and 25 cells, respectively). At 20 weeks of gestation, labour was induced because of fetal death in utero. An autopsy performed on the fetus revealed a male phenotype. Placenta and fetal...
Topics
- Adult
- Chorionic Villi Sampling
- Chromosome Aberrations
- Chromosome Disorders
- Diagnostic Errors
- Female
- Fetal Death
- Humans
- Karyotyping
- Phenotype
- Pregnancy
- Pregnancy, Multiple