Article
Effect of treatment on biclonal gammopathy associated with Gaucher disease.
Journal of inherited metabolic disease - 1 Oct 2007
Decaux O, Ruelland A, Grosbois B
Abstract excerpt
The non-random association of Gaucher disease with polyclonal and monoclonal gammopathy has been known since 1950. The effect of treatment on monoclonal gammopathy is not well documented. We report on the long-term evolution of a biclonal gammopathy in a patient with type I Gaucher disease who was treated with splenectomy and enzyme replacement therapy. A 44-year-old man presented with hepatomegaly and massive...
Topics
- Adult
- Gaucher Disease
- Glucosylceramidase
- Hexosaminidases
- Humans
- Male
- Mutation
- Paraproteinemias
- Recombinant Proteins
- Splenectomy
- Treatment Outcome
- gamma-Globulins
