Article
HLA-DQB1 0602 allele is associated with splenomegaly in Japanese sarcoidosis.
Journal of internal medicine - 1 Oct 2007
Sato H, Nagai S, du Bois R M, Handa T, Suginoshita Y, Ohta K, Welsh K I, Izumi T
Abstract excerpt
OBJECTIVES: The association between HLA class II alleles and susceptibility to sarcoidosis is well documented. Further, the HLA-DRB1 15 and DQB1 0602 haplotype has been considered as a marker for both chronic and severe disease. Splenomegaly has been proposed as a marker for severity and activity...
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