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Article

Important changes in biochemical properties and function of mutated LLP12 domain of HIV-1 gp41.

Chemical biology & drug design - 1 Oct 2007

Zhu Yun, Lu Lu, Chao Lijun, Chen Ying-Hua

Abstract excerpt

The human immunodeficiency virus type 1 gp41 possesses an unusually long and conserved cytoplasmic region. Mutations in the LLP12 domain in this region have been shown to significantly affect viral competence. It is likely that the impaired infectivity of this mutated virus involves certain biochemical aspects of the peptide LLP12. To test our assumptions, some important biochemical properties and functions of...

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Identifiers

PMID: 17850282
DOI: 10.1111/j.1747-0285.2007.00564.x
PMCID: PMC7188357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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