Article
Quantitative and qualitative in vitro analysis of the stem cell potential of hematopoietic cells purified from murine skeletal muscle.
Cell research - 1 Sept 2007
Haond Celine, Farace Françoise, Guillier Martine, Lécluse Yann, Mazurier Frederic, Vainchenker William, Turhan Ali G
Abstract excerpt
The murine skeletal muscle contains hematopoietic stem cells, but this potential has so far not been studied quantitatively or qualitatively in vitro. To quantify the hematopoietic stem cell potential, we have used highly purified SP/CD45(+) cells in long-term culture initiating cell (LTC-IC) assays. The SP/CD45(+) cell population purified from murine muscle was found to have significant stem cell activity with...
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