Article
Frequency of HLA-DQA1 alleles in the Japanese population.
Human heredity - 1 Jan 1991
Tamaki K, Yamamoto T, Uchihi R, Katsumata Y, Kondo K, Mizuno S, Kimura A, Sasazuki T
Abstract excerpt
One of the HLA class II genes, HLA-DQA1, was typed from 290 unrelated healthy Japanese using the oligonucleotide typing method. The HLA-DQA1 gene was enzymatically amplified and typed by dot-blot hybridizations with 10 sequence-specific oligonucleotide probes labeled nonradioactively. Using this method, the HLA-DQA1 genotype was theoretically classified into 36 genotypes: 8 homozygous and 28 heterozygous ones....
Topics
- Alleles
- Base Sequence
- Blood Stains
- DNA
- DNA Probes
- Gene Frequency
- Genotype
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Humans
- Japan
- Molecular Sequence Data
