Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diagnostic value of serum immunoglobulinaemia D level in patients with a clinical suspicion of hyper IgD syndrome.

Rheumatology (Oxford, England) - 1 Oct 2007

Ammouri W, Cuisset L, Rouaghe S, Rolland M-O, Delpech M, Grateau G, Ravet N

Abstract excerpt

OBJECTIVE: The hyperimmunoglobulinaemia D and periodic fever syndrome (HIDS) was originally defined by the presence of a high serum level of immunoglobulin D associated with recurrent fever. Since the discovery of the mevalonate kinase gene (MVK) gene encoding the mevalonate kinase enzyme, most patients with a clinical diagnostic of HIDS are now found to have a mevalonate kinase deficiency based on metabolic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Familial Mediterranean Fever

Share to Immunoglobulin D

Share to Mevalonate Kinase Deficiency

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 17804452
DOI: 10.1093/rheumatology/kem200

Genes

MVK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diagnostic value of serum immunoglobulinaemia D level in patients with a clinical suspicion of hyper IgD syndrome.PMID 17804452Read ↗

Mevalonate kinase genotype in children with recurrent fevers and high serum IgD level.Semantic proximity Read ↗

Clinical and molecular variability in childhood periodic fever with hyperimmunoglobulinaemia D.Semantic proximity Read ↗

Molecular analysis of the mevalonate kinase gene in a cohort of patients with the hyper-igd and periodic fever syndrome: its application as a diagnostic tool.Semantic proximity Read ↗

[Periodic fever with increased IgD].Semantic proximity Read ↗

Molecular analysis of MVK mutations and enzymatic activity in hyper-IgD and periodic fever syndrome.Semantic proximity Read ↗

[MVK gene abnormality and new approach to treatment of hyper IgD syndrome and periodic fever syndrome].Semantic proximity Read ↗

[Hyperimmunoglobulinemia D and periodic fever syndrome. A phenotypical analysis of a Spanish family].Semantic proximity Read ↗

Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a heterozygous MVK carrier possibly influences the phenotype of hyperimmunoglobulinemia D with periodic fever syndrome or vice versa.Semantic proximity Read ↗

[Utility of denaturing high performance liquid chromatography (DHPLC) for the diagnosis of mevalonate kinase deficiency in periodic disease].Semantic proximity Read ↗

Homozygous V377I mutation causing mevalonate kinase.Semantic proximity Read ↗

A patient with hyper-IgD syndrome responding to anti-TNF treatment.Semantic proximity Read ↗

MVK mutations and associated clinical features in Italian patients affected with autoinflammatory disorders and recurrent fever.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.