Article
Note on the computation of critical effective population sizes.
Journal of computational biology : a journal of computational molecular cell biology - 1 Sept 2007
Zhang Liqing, Watson Layne T
Abstract excerpt
This work extends the work of Whitlock in examining the critical effective population sizes from the fixation of both deleterious and beneficial mutations under drift and selection to prevent mutation breakdown of the population. The validity of approximations for the probability of fixation depends on the nature of the assumed distribution for the fitness effect of both types of mutations. Using no approximation...
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