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Article

Extra small marker chromosome associated with normal phenotype due to 3:1 disjunction of t(14;22) in a parent. Implications for the origin of marker chromosomes.

Clinical genetics - 1 Sept 1991

Bröndum-Nielsen K

Abstract excerpt

A family with segregation of a translocation t(14;22) (q31;q11) is is reported. The proband was ascertained by chromosome analysis after repeated spontaneous abortions in his wife. His normal sister was found to have the karyotype 47,XX,+ der (22). The small size and banding pattern of chromosome 22 make it difficult to determine the breakpoint with certainty, but it was judged to be at q11. This small marker...

Topics

Abortion, Spontaneous
Chromosome Aberrations
Female
Genetic Markers
Humans
Karyotyping
Male
Pedigree
Phenotype
Pregnancy
Translocation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1773537
DOI: 10.1111/j.1399-0004.1991.tb03079.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1773537-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Extra small marker chromosome associated with normal phenotype due to 3:1 disjunction of t(14;22) in a parent. Implications for the origin of marker chromosomes.PMID 1773537Read ↗

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