Article
Prenatal detection and characterization of a small supernumerary marker chromosome (sSMC) derived from chromosome 22 with apparently normal phenotype.
Prenatal diagnosis - 1 Oct 2006
Lin Chyi-Chyang, Hsieh Yao-Yuan, Wang Chung-Hsing, Li Yueh-Chun, Hsieh Lie-Jiau, Lee Chien-Chung, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
OBJECTIVE: To present prenatal findings and molecular cytogenetic characterization of a small supernumerary marker chromosome (sSMC) derived from chromosome 22 with apparently normal phenotype. CASE AND METHODS: An amniocentesis was performed at 15 weeks' gestation and a small marker chromosome in the female fetus of a twin pregnancy was noted. A second amniocentesis was performed at 18 weeks; G-banding analysis...
Topics
- Adult
- Amniocentesis
- Aneuploidy
- Chromosome Banding
- Chromosomes, Human, Pair 22
- Female
- Genetic Markers
- Humans
- In Situ Hybridization, Fluorescence
- Karyotyping
- Phenotype
- Pregnancy
- Pregnancy Outcome