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Article

Functional roles of Fli‐1, a member of the Ets family of transcription factors, in human breast malignancy

28 Aug 2007

Abstract excerpt

The Ets family of transcription factors is implicated in malignant transformation and tumor progression, including invasion, metastasis and neo-angiogenesis. In the present study, we found that the Fli-1 gene, a member of the Ets family, was highly expressed in several breast cancer cell lines (MDA-MB231, MDA-MB436, BT-549 and HCC1395). To investigate the functional roles of Fli-1 in breast cancer malignancy, we...

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PMID: 17727680
DOI: 10.1111/j.1349-7006.2007.00598.x

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