Article
[Impact of M. tuberculosis genotype on survival in mice with experimental tuberculosis].
Problemy tuberkuleza i boleznei legkikh - 1 Jan 2007
Andreevskaia S N, Chernousova L N, Smirnova T G, Larionova E E, Kuz'min A V
Abstract excerpt
To study the virulence of Mycobacterium tuberculosis strains of the W cluster, C57B1/6 mice were intravenously inoculated with a lethal dose (5x10(6) CFU) of 14 clinical M. tuberculosis strains (11 drug-sensitive and 3 multidrug-resistant) belonging to different RFDP IS6110 genotypic clusters and two laboratory M. tuberculosis strains H37Rv and H37Ra. The virulence was evaluated by the survival of mice after...
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