Article
Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene.
Gene - 15 Oct 2007
Gérard Marie-Aline, Krol Alain, Carbon Philippe
Abstract excerpt
The mitochondrial transcription factor A (Tfam) is essential for transcription initiation and replication of mitochondrial DNA. It was previously reported that transcription factors Sp1, NRF-1, NRF-2 were critical for maintaining the normal transcription levels of the mammalian TFAM gene. In this work, investigation of the transcriptional regulation of the human TFAM gene revealed the presence of two...
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