Article
Molecular profiling and genomic microarrays in prostate cancer.
Experimental oncology - 1 Jun 2007
Golias Ch, Charalabopoulos A, Stagikas D, Giannakopoulos X, Peschos D, Batistatou A, Sofikitis N, Charalabopoulos K
Abstract excerpt
In the present review article a global approach regarding the usefulness of genomic microarrays in prostate cancer management, is attempted. Cancer is a multistep process of mutations in key regulatory genes and epigenetic alterations that result in loss of balanced gene expression. A complete knowledge of the interaction between the genetic variability of the neoformation (tumor profiling) and the genetic...
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