Article
A WD40 domain cyclophilin interacts with histone H3 and functions in gene repression and organogenesis in Arabidopsis.
The Plant cell - 1 Aug 2007
Li Hong, He Zengyong, Lu Guihua, Lee Sung Chul, Alonso Jose, Ecker Joseph R, Luan Sheng
Abstract excerpt
Chromatin-based silencing provides a crucial mechanism for the regulation of gene expression. We have identified a WD40 domain cyclophilin, CYCLOPHILIN71 (CYP71), which functions in gene repression and organogenesis in Arabidopsis thaliana. Disruption of CYP71 resulted in ectopic activation of homeotic genes that regulate meristem development. The cyp71 mutant plants displayed dramatic defects, including reduced...
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