Article
Number of STR repeats as a potential new quantitative genetic marker for complex diseases, illustrated by schizophrenia.
Biochemical genetics - 1 Oct 2007
Liu Hui, Yu Weijian, Wang Xuebin, Fang Fang, Yang Guang, Zhou Jie, Liang Xiaohua, An Wanxin
Abstract excerpt
It has proved difficult to find strong and replicable genetic linkages for complex diseases, since each susceptibility gene makes only a modest contribution to onset. This is partly because high-efficacy genetic markers are not usually available. The aim of this article is to explore the possibility that the total number of tandem repeats in one STR locus, rather than the frequencies of different alleles, is a...
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