Article
Mechanisms of scleroderma-induced lung disease.
Proceedings of the American Thoracic Society - 15 Aug 2007
du Bois Roland M
Abstract excerpt
Scleroderma (systemic sclerosis) is characterized by dermal thickening and is subclassified, on the basis of the pattern of skin involvement, as diffuse or limited cutaneous disease. The lung fibrosis associated with systemic sclerosis is histopathologically nonspecific interstitial pneumonia and occurs to various extents. A key determinant of the development of lung fibrosis is the carriage of the anti-DNA...
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